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Iconic Innovation and Landmark Luxury: The 2025 Mercedes-Benz E 450 4MATIC® Sedan

A split pane view of the front and rear exterior of the 2025 Mercedes-Benz E 450 4MATIC® Sedan near Scottsdale

2025 Mercedes-Benz E 450 4MATIC® Sedan near Scottsdale 

The 2025 Mercedes-Benz E 450 4MATIC® Sedan brings together elegance, intelligence, and dynamic performance in a way that defines modern luxury. With a refined design, advanced technology, and an exhilarating driving experience, this sedan sets a new standard. At Mercedes-Benz of Scottsdale, we are excited to offer this remarkable vehicle to drivers seeking the perfect balance of sophistication and power.

View Our E-Class Inventory

A Dynamic Driving Experience 

The 2025 Mercedes-Benz E 450 4MATIC® Sedan performance delivers both precision and power. A 3.0L inline-6 turbo engine with a mild hybrid drive provides a thrilling combination of responsiveness and efficiency. Producing 375 horsepower and 369 lb-ft of torque, this sedan offers smooth acceleration and a refined ride. 

Moreover, the integrated starter-generator enhances fuel economy by adding up to 23 horsepower and 151 lb-ft of torque when needed. This system also supports gas-free coasting and energy recuperation during deceleration. Additional performance features include: 

  • AGILITY CONTROL® selective damping – Adjusts suspension settings for a more responsive or comfortable ride based on road conditions. 
  • Available AIRMATIC® suspension – Uses electronically controlled air springs for a balance of smoothness and handling. 
  • 4MATIC® all-wheel drive – Enhances stability and traction in various road conditions, ensuring confidence in every drive*. 

This blend of engineering and technology allows the E 450 4MATIC® to deliver an engaging, confident ride, whether cruising through Scottsdale or tackling winding roads. 

A split pane view of the front and rear exterior of the 2025 Mercedes-Benz E 450 4MATIC® Sedan near Scottsdale
The cockpit, controls, and displays in the 2025 Mercedes-Benz E 450 4MATIC® Sedan near Scottsdale

Advanced Design with Classic Appeal 

The exterior of the 2025 Mercedes-Benz E 450 4MATIC® Sedan showcases a blend of athleticism and elegance. A long hood, short deck, and sculpted lines emphasize its sporty yet sophisticated presence. The iconic grille, accented by the Mercedes-Benz emblem, enhances its unmistakable appeal. LED headlights and taillights further contribute to its modern yet timeless look. 

Inside, the cabin combines cutting-edge technology with traditional craftsmanship. Premium materials like Natural Grain Black Ash wood trim and hand-fitted upholstery create a refined atmosphere. The available MBUX Superscreen extends the digital display across the dashboard, integrating seamlessly with driver and passenger controls.

The luxurious front seats in the 2025 Mercedes-Benz E 450 4MATIC® Sedan
A front quarter exterior view of the 2025 Mercedes-Benz E 450 4MATIC® Sedan

Intelligent Technology at Your Fingertips 

Technology in the 2025 Mercedes-Benz E 450 4MATIC® Sedan luxury experience revolves around personalization and convenience. The Mercedes-Benz User Experience (MBUX) system responds to natural voice commands, making it easier than ever to adjust settings. A driver-facing camera helps personalize seating and display settings while monitoring alertness. 

Other standout features include: 

  • Panorama roof – Provides an expansive view and enhances cabin openness. 
  • ENERGIZING Comfort PLUS (optional) – Combines ambient lighting, climate control, and massage seats to create a relaxing or invigorating atmosphere. 
  • FrontBass system – Uses the car’s frame as a resonance chamber for deeper, more immersive sound. 

From daily commutes to weekend getaways, these innovations ensure every journey is as enjoyable as it is effortless.

Find the 2025 Mercedes-Benz E 450 4MATIC® Sedan Near Scottsdale 

For those searching for a 2025 Mercedes-Benz E 450 4MATIC® Sedan for sale, Mercedes-Benz of Scottsdale offers an exceptional selection. With cutting-edge performance, luxurious comfort, and intelligent technology, this sedan represents the pinnacle of modern driving. Visit our dealership today to explore its features firsthand and experience why this model stands out in the luxury sedan market. 

Interested in a Mercedes-Benz E 450 4MATIC® Sedan?
30 Results
2019 Mercedes-Benz E-Class E 300 RWD Sedan
2019 Mercedes-Benz E-Class E 300 RWD Sedan
42 Interested, Peoria, AZ, 2.0L Inline-4 Turbo, E 300 RWD Sedan, Automatic, # B3786, 9G-TRONIC Automatic -inc: Steering Wheel Shift Paddles, Rear Wheel Drive, 21/29 mpg
Mileage 53,369
Engine 2.0L Inline-4 Turbo
Transmission Description 9G-TRONIC Automatic -inc: Steering Wheel Shift Paddles
Fuel Economy 21/29
Price
$53,500
Retail Price
$26,165
DetailsShow selling price
2022 Mercedes-Benz E-Class E 350 Sedan
2022 Mercedes-Benz E-Class E 350 Sedan
35 Interested, Scottsdale, AZ, 2.0L Inline-4 Turbo Engine, E 350 Sedan, Automatic, # P8207, 9G-TRONIC Automatic, Rear Wheel Drive, 23/31 mpg
Mileage 27,358
Engine 2.0L Inline-4 Turbo Engine
Transmission Description 9G-TRONIC Automatic
Fuel Economy 23/31
Price
$38,991
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 RWD Sedan
2026 Mercedes-Benz E-Class E 350 RWD Sedan
12 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 RWD Sedan, Automatic, # A18066, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$66,900
DetailsShow selling price
2025 Mercedes-Benz E-Class E 350 Sedan
2025 Mercedes-Benz E-Class E 350 Sedan
51 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # A17824, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$66,945
DetailsShow selling price
2025 Mercedes-Benz E-Class E 350 Sedan
2025 Mercedes-Benz E-Class E 350 Sedan
17 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # A17825, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$66,945
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
7 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # A18023, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$68,915
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25979, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$69,905
DetailsShow selling price
2025 Mercedes-Benz E-Class E 450 4MATIC® Sedan
2025 Mercedes-Benz E-Class E 450 4MATIC® Sedan
43 Interested, Peoria, AZ, 3.0L I6 Turbo w/48V Mild Hybrid System, E 450 4MATIC® Sedan, Automatic, # RA17100, 9G-TRONIC 9-Speed Automatic, All Wheel Drive, 22/31 mpg
Mileage 7,425
Engine 3.0L I6 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Fuel Economy 22/31
Price
$73,565
Retail Price
$70,307
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 RWD Sedan
2026 Mercedes-Benz E-Class E 350 RWD Sedan
5 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 RWD Sedan, Automatic, # A18035, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$70,535
DetailsShow selling price
2025 Mercedes-Benz E-Class E 450 4MATIC® Sedan
2025 Mercedes-Benz E-Class E 450 4MATIC® Sedan
32 Interested, Peoria, AZ, 3.0L I6 Turbo w/48V Mild Hybrid System, E 450 4MATIC® Sedan, Automatic, # RA16886, 9G-TRONIC 9-Speed Automatic, All Wheel Drive, 22/31 mpg
Mileage 5,234
Engine 3.0L I6 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Fuel Economy 22/31
Price
$74,525
Retail Price
$71,214
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
41 Interested, Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25776, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$72,000
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25905, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$73,180
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
18 Interested, Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25837, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$73,570
DetailsShow selling price
2025 Mercedes-Benz E-Class E 350 RWD Sedan
2025 Mercedes-Benz E-Class E 350 RWD Sedan
2 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 RWD Sedan, Automatic, # RA17398, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Mileage 3,761
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Fuel Economy 25/33
Price
$78,595
Retail Price
$75,061
DetailsShow selling price
2025 Mercedes-Benz E-Class E 350 Sedan
2025 Mercedes-Benz E-Class E 350 Sedan
44 Interested, Peoria, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # A17822, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$75,280
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
32 Interested, Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25670, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$76,405
DetailsShow selling price
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
1 Interested, Peoria, AZ, 3.0L I6 Turbo Mild Hybrid -inc: 48V (375 hp, 369 lb-ft), E 450 4MATIC® All-Terrain Wagon, Automatic, # RA17182, 9-Speed Automatic 9G-TRONIC, All Wheel Drive, 22/31 mpg
Mileage 3,656
Engine 3.0L I6 Turbo Mild Hybrid -inc: 48V (375 hp, 369 lb-ft)
Transmission Description 9-Speed Automatic 9G-TRONIC
Fuel Economy 22/31
Price
$82,585
Retail Price
$78,831
DetailsShow selling price
2026 Mercedes-Benz E-Class E 350 Sedan
2026 Mercedes-Benz E-Class E 350 Sedan
31 Interested, Scottsdale, AZ, 2.0L I4 Turbo w/48V Mild Hybrid System, E 350 Sedan, Automatic, # M25779, 9G-TRONIC 9-Speed Automatic, Rear Wheel Drive, 25/33 mpg
Engine 2.0L I4 Turbo w/48V Mild Hybrid System
Transmission Description 9G-TRONIC 9-Speed Automatic
Drivetrain Rear Wheel Drive
Fuel Economy 25/33
MSRP
$79,450
DetailsShow selling price
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
35 Interested, Scottsdale, AZ, 3.0L I6 Turbo Mild Hybrid -inc: 48V (375 hp, 369 lb-ft), E 450 4MATIC® All-Terrain Wagon, Automatic, # M24823, 9-Speed Automatic 9G-TRONIC, All Wheel Drive, 22/31 mpg
Engine 3.0L I6 Turbo Mild Hybrid -inc: 48V (375 hp, 369 lb-ft)
Transmission Description 9-Speed Automatic 9G-TRONIC
Drivetrain All Wheel Drive
Fuel Economy 22/31
MSRP
$80,345
DetailsShow selling price
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
2025 Mercedes-Benz E-Class E 450 4MATIC® All-Terrain Wagon
51 Interested, Scottsdale, AZ, 3.0L I6 Turbo Mild Hybrid Engine, E 450 4MATIC® All-Terrain Wagon, Automatic, # M25354, 9-Speed Automatic 9G-TRONIC, All Wheel Drive, 22/31 mpg
Engine 3.0L I6 Turbo Mild Hybrid Engine
Transmission Description 9-Speed Automatic 9G-TRONIC
Drivetrain All Wheel Drive
Fuel Economy 22/31
MSRP
$80,345
DetailsShow selling price
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*Best performance on snow and ice obtained with winter tires. Please always drive carefully, consistent with road conditions.